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    • MIDTERM 2 STUDY GUIDE
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      • Module 1 Assignments
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    • Biomes
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    • Symbiosis
    • Population Ecology
    • Competition in Nature
    • Herbivory
    • Niches
    • Fossil Fuels
  • Environmental Biology Laboratory
    • SOILS AND GROUNDWATER
    • Ecological Roles of Living Organisms
      • The Basics
      • Bacteria - Ecological Roles
      • Protists - Ecological Roles
      • Fungus - Ecological Roles
      • Plantae and Animalia - Ecological Roles
    • Virtual FIELD TRIP TO THE RIO HONDO COLLEGE ​WILDLIFE SANCTUARY - Adaptations to Dry Climates
    • Microscopic Plant Adaptations
    • Natural Selection
    • GROWTH CURVES
    • SOILS AND GROUNDWATER
    • LC50 and LD50
    • How to Make a Solar Water Heater
    • WATER QUALITY ANALYSIS
  • General Biology
    • Characteristics of Life
    • Chemistry of Life - Inorganic
    • The Chemistry of Cells - ORGANIC
    • Introduction to The Cell
    • Photosynthesis and cellular Respiration
    • Cell Membranes and Osmosis
    • The Cell Cycle
    • REGULATION of The Cell Cycle
    • Mitosis
    • Meiosis
    • The Structure of DNA
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    • GENERAL BIOLOGY 101 LABORATORY HOME PAGE
      • Enzymes
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      • Lab 1 - Bacteria, Protista and Fungi
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      • Lab 8 - Enzymes
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      • Lab 10 Fermentation, Aerobic Cellular Respiration and Associated Major Organ Systems
    • GENERAL BIO 1110L Labs
      • lab 2 - CELLS - BIO 111L
      • lab 3 - DIFFUSION and OSMOSIS - BIO 111L
      • lab 4 - The Circulatory System - BIO 111L
      • lab 6 - Photosynthesis and Cellular Respiration
      • lab 7 - Reproduction - BIO 111L
      • DNA, GENES AND GENETIC INHERITANCE
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  • Human Biology
    • A History of Human Biology
    • Levels of Organization
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    • Cells
    • Cartilage SAC
    • BONES AND SKELETAL TISSUES
  • Human Biology Lab
    • Testing for Sugar, Starch and Proteins
    • Osmosis, Diffusion and Filtration
    • buffers
    • OSMOSIS LAB
    • Anatomical Planes
    • Body Cavities and Membranes
    • Anatomical Positions
    • The Appendicular Skeleton
    • The SKULL
    • the Thoracic Cage
    • the vertebral column
  • Human Sexuality
    • Course Information
    • Course Calendar
    • Lesson 1 - Introduction to Human Sexuality
    • Lesson 2 - Genetic Inheritance of Human Sexuality
    • Lesson 3 - The Male Reproductive Tract
    • Lesson 4 - The Female Reproductive Tract
    • Lesson 5 - The Menstrual Cycle
    • Midterm Exam Study Guide
    • Lesson 6 - Fetal Development and Sexual Differentiation
    • Lesson 7 - Disorders of Sexual Development
    • Lesson 8 - Gender Identity and Sexual Attraction
    • Lesson 9 - Fetishism
    • Lesson 10 - Sexuality Throughout the World
    • ​Lesson 11 - Sexuality Through the Ages
    • Lesson 12 - Sexual Harassment, Coercion and Violence
    • Final Exam Study Guide
  • Microbiology PORTAL
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      • Diseases
      • EPIDEMIOLOGY
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      • Bacteria versus Archaea
      • Intro. to Bacteria
      • Viruses and Prions
      • Microbial Genetics
      • Microbial Nutrition and Growth
        • Nutritional Categories
        • Microbial Metabolism
        • CONTROL OF BACTERIA GROWTH AND ANTIBIOTICS
      • Eukaryotic Organisms
      • Archaeal Diversity
      • Prokaryotic and Eukaryotic Cells
      • Bacteria vs Archaeal Structures
      • Taxonomic Classifications
      • Archaea, Bacteria and Eukaryotic Cells
      • MIC- CPP Course Calendar
    • Cell Theory
    • Chemistry of Life
      • Chemical Bonds
      • Chemical Reactions
    • Biofilms
    • Definition of Terms
  • Microbiology Laboratory
    • Cell Culture and Inoculations
    • aseptic technique
    • WET MOUNT
    • Streak Plate
    • Mannitol salt agar (MSA) Test
    • Eosin Methylene Blue (EMB)
    • Blood Agar
    • Dilution Series and Calculations
    • Phage Plaque Assay
    • MICROBIOLOGY UNKNOWN LAB
    • Microbiology Lab -study guide exam one
    • Ex 2 - Microorganisms
    • EX 3 - aseptic technique
    • Ex 4 - Smear Prep
    • Ex 5 - Simple Stains
    • Ex 6 - Negative Staining
    • Ex 8 - Gram Stain
    • Ex 9 - Acid-Fast Stain
    • Ex 10 - Endospore Stain
    • Ex 11 - Motility Test
    • ex 12 -​ Pure culture technique
    • ex 13 - UV Radiation
    • Ex 14 - Enumeration of Bacteria : Standard Plate Count
    • ex - 15 Effects of Temperature on Growth
    • ex 16 - Hand-washing
    • ex 17 - pH and microbial growth
    • ex 18 - Evaluation of Antiseptics
    • ex 19 - Antibiotic Sensitivity : Kirby-Bauer Method
  • HISTOTECHNOLOGY
  • The Brain
  • The Brain
  • The Structure of DNA
  • Contact
  • FUN ZONE
    • GAMES
    • Video Vault
    • Population Ecology - ACTIVITY
    • The Carbon Cycle - ACTIVITY
    • Evolution - ACTIVITY
    • The Cell Game
    • SYMBIOSIS ACTIVITY
    • THE LORAX ACTIVITY
    • Brittney the Kidney
    • From Soup to Poop
    • MITOSIS - THE NURSERY RHYME
    • Verne the Sperm and friends
      • Verne the Sperm pg1
        • Verne the Sperm pg2
        • Verne the Sperm pg3
        • Verne the Sperm pg4
        • Verne the Sperm pg5
  • Lab 6 - The Chemistry of Cells
  • A History of Anatomy
  • List of Pages
    • Microscopes
  • Cell Membranes and Osmosis
  • Chemistry of Life
  • Muscle Movements
  • The Muscles of the Head, Trunk and Shoulders
  • The Muscles of the Limbs
  • Nervous Tissue
  • The Brain - Anat and Physiology
  • Instructions for Taking BIO 3070
  • MTH 121 Algebra A - Course Schedule and Info
  • Laboratory Calendar CMC Spring 2019
  • Genetics Lab
  • Chemistry and Conversions Lab
  • Digestion and Enzymes Lab
  • Endocrine and Homeostasis Lab
  • Muscles and Reflexes Lab
  • Sensory Lab
  • Immunohistochemistry
  • Blood Lab
  • Heart Rate, Blood Pressure, Electrocardiogram Lab
  • Respiratory Lab
  • Lab 11 Renal Lab
  • Blood Typing Game
  • Body Systems Interactive
  • Ch 9 - The Central Nervous System
  • Ch 10 - Sensory Systems
  • Neuron Virtual Laboratory
  • Virtual Eye Lab
  • Virtual pH Lab
  • Chemical Bonds Virtual Lab
  • Beer's Law Virtual Lab
  • Build-an-Atom Virtual Lab
  • Diffusion Virtual Lab
  • Ohm's Law Virtual Lab
  • New Page
  • Ch 8 - Nervous System

BONES AND SKELETAL TISSUES

BONES AND SKELETAL TISSUES

Cartilage of the Skeleton

Picture
Cartilage of our skeleton can be categorized either by their histological features, or by their location in the body.

Cartilage is a connective tissue that is separated into 3 main types;
  1. Hyaline Cartilage, - The majority of our cartilage is hyaline cartilage. It provides a smooth surface within our joints for movement. 
  2. Elastic Cartilage - The rarest type of cartilage is elasic cartilage. It forms the external portions of our ears and our epiglottis, which acts to keep food out of your trachea.
  3. Fibrocartilage. - The strongest cartilage in our bodies is fibrocartilage. This cartilage is found in areas of our body that undergo a lot of mechanical stress due to compression and tension forces, like our knee joints and invertebral discs. 

 The human body has 3 categories of cartilage based on their location.
  1. Articular Cartilage – covers the ends of most bones
  2. Costal Cartilage – connects the ribs to the sternum
  3. Respiratory Cartilage – makes up the larynx and epiglottis and reinforces air passages

Picture

​Cartilage is a connective tissue consisting chondrocytes and a dense matrix of collagen fibres and elastic fibers and a calcified ground substance. The matrix is produced by chondroblasts (immature chondrocytes). 

The surfaces of most of the cartilage in your body is surrounded by a membrane of dense irregular connective tissue called perichondium.   Chondrocytes that are outside of the perichondrium are surrounded by a space called a lacuna (lacunae for plural).  Chondroblasts that exist in the perichondrium don't have lacunae.

Cartilage does not contain blood vessels or nerves except for the area of he perichondrium. 



Cartilage Comes Before Bone

    All of your bone started out as cartilage before you were born. A lot of this cartilage is converted into spongy bone and then much of the spongy bone gets replaced by compact bone. As an adult, only 20% or so of your bone remains as spongy bone. The spongy bone of an adult can be found in the center of the long bones in the arms and legs, as well as the pelvic bones, ribs, skull, and the vertebrae in the spinal column.


BONE TISSUE

The Two Types of Bone Tissues; Spongy and Compact

Picture

Bones consist of two types of osseous tissue; spongy bone and compact bone. These two bone tissue types work together in each bone and provide complementary functions. Compact bone is the hard outer portion of the bone, and spongy bone is the spongy, honeycomb-like bone tissue that is found at the ends of long bones and in the middle of your vertebrae.

e.

Spongy (Cancellous) Bone

Picture
The internal portions of your bones contain spongy bone, also called trabecular bone or cancellous bone. Spongy bone is easily recognized by its honeycomb, spongy structure of small  pointy or flat pieces called trabeculae.  The open spaces between the trabeculae are filled with red or yellow bone marrow.

     Spongy bone lives up to its name in its appearance. It looks 'spongy'. Some people describe the appearance of spongy bone to be similar to a honeycomb. Spongy bone is made up of trabeculae,
which has many open spaces connected by flat planes. 

    Spongy bone is made up of trabeculae. At the ends of long bones like the femur, the bone is actually not solid but is full of holes that are connected to each other by thin rods and plates of bone tissue known as trabeculae.
Slide of Spongy Bone
Picture

Animation of Spongy Bone Trabeculae

via GIPHY


Compact (Cortical) Bone

Picture
Compact (cortical) bone more dense and strong. It's primary purpose is to provide structural support for the body. Compact bone is made up of osteons which can be visualized on the slide below. This slide shows a cross-section  of the femur (bone of upper leg), which is the longest bone in the human body. The circular pattern seen on a slide of bone tissue are osteons. 

 Each osteon consists of ringed layers, or lamellae, of compact bone tissue that surround a central canal (Haversian canal). The central canal (a.k.a. Haversian canal) contains the bone's nerve and blood supplies.

Osteons are units of collagen tubes within other collagen tubes. Osteons allow bones to resist twisting stress.

Click on the short video below, to learn more about the structure of osteons. 

Video of Osteon Model
courtesy of   https://youtu.be/As8oqkMDoT4 


 - Bone Classifications -

Classifications of Bones by Location

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​Our skeleton is divided into 2 main regions;

1) the axial skeleton
2) the appendicular skeleton
​
The axial skeleton has 80 named bones and consists of the skull, vertebral column, and rib cage.

The appendicular skeleton contains 126 named bones. It includes the the upper and lower limbs, pectoral (shoulder) girdle, and pelvic (hip) girdle.


​The human body has 206 named bones total.

Classifications of Bones by Shape

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Long Bones

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Long bones are longer than they are wide. Long bones string, dense bones that provide strength, structure, and mobility to the body.

Great examples of long bones can be seen in the arms (humerus, ulna and radius) and legs (femur, tibia and fibula) of your skeleton.  



- Keep in mind, a bone can be considered a long bone, even if it is small. As long as it is much longer than it is wide, it qualifies as a "long bone"
     
​     For example, s
ome bones in the fingers are small, but they are classified as long bones. 

FUN FACT
: The Femur is the Longest Bone of the Body. ​

Long bones are some of the longest bones in the body, such as the Femur, Humerus and Tibia but are also some of the smallest including the Metacarpals, Metatarsals and Phalanges.

Short Bones

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    Short bones appear somewhat cube-shaped. Short bones are defined as being approximately as wide as they are long They are roughly as long as they are wide.  

    Short bones function to provide support and stability with little to no movement.They allow for multi-directional movement and flexibility.

    We have short bones located in our ankles (tarsal bones) and wrists (carpal bones).

​Several short bones, called carpal bones, make up our wrists. This allows for a good range of motion without needing a lot of motion at any one joint.

via GIPHY

Short bones have a thin layer of compact bone with spongy bone inside. They also contain relatively large amounts of bone marrow.
Flat Bones
Flat bones appear as broad, and flat plates. Flat bones function to add a hard shield of protection for vital internal structures or to provide a large, broad surface for muscle attachment. Flat bones are especially strong. Some great examples of flat bone in your skeleton include the shoulder blade (scapula), the Sternum (breast bone), the cranium (skull), the pelvis and the ribs. The anterior and posterior surfaces of flat bones are composed of compact bone to provide strength and protection. The inner portion of long bones contains spongy bone which has the bone marrow.   FUN FACT: In adults, the highest number of red blood cells are formed in flat bones. 
Flat bones are wide and flat. We have flat bones that make up the cranial bones of the skull, the scapulae, the pelvis, the sternum and the rib cage. 
Irregular Bones
Some bones are oddly shaped and do not fit into the other categories of bone ("Long", "Short" or "Flat"). These bones have a category all their own, called irregular bone.  These bones have a non-uniform shape. 
 The irregular bones of your body includes your vertebrae, facial bones, the mandible, the sacrum and the hyoid bone (assists in swallowing). They primarily consist of cancellous bone, with a thin outer layer of compact bone.
Sesamoid Bones
Sesamoid bones are short or irregular bones that are embedded in a tendon. The best example of a sesamoid bone is the patella. The patella is not attached to the other bones in the joint. Instead, it is attached to the tendon. This allows your patella (known commonly as your knee cap) to glide along the distal edge of the femur.  Other sesamoid bones can be found in your smallest carpel and metatarsals. Sesamoid bones function in the body to to protect the tendon by creating a strong surface that can better withstand friction. 
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Sutural Bones
Most textbooks leave out the category of "sutural bone", and for good reason. The other classifications of bones discussed on this page are based solely on the shape (or morphology) of the bone itself. The category or classification of sutural bone refers to bones in a specific location within the skeleton. Sutural bones (sometimes called Wormian bones) are the specific bones of the skull that come together and form extra bone pieces that occur within a suture (joint) in the cranium. These are irregular isolated bones that appear in addition to the usual centers of ossification of the cranium and, although unusual, are not rare.
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Summary Table of Bone Classifications

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Is a Bone a Tissue or an Organ?  
The answer i
s...  YES!

Bones are considered a tissue and an organ. Remember... An organ is made of different tissue types which come together to form a unit that has a specific function in the body. Even though our bones consist primarily of osseous tissue, they  also contain nervous tissue in their nerves, fibrous tissue lining their cavities, and muscle and epithelial tissue in their blood vessels. 

BONE AS A TISSUE: Bone tissue (or osseous tissue)  is a type of connective tissue. Osseous tissue consists primarily of osteoblasts which makes the proteins and molecules needed to form the fibers and the ground substance which makes up the extracellular matrix. 

BONE AS AN ORGAN: When we refer to bones as an organ, we include not only the osseous tissue, but also the cartilage, nervous tissue, the epithelial tissue (in the form of blood vessels) and the fibrous connective tissue  that functions together as a unit. A bone is an organ that makes up a large portion of the human skeleton. Bones function in your body to support and protect your internal organs and to allow for mobility. Bones also store vital minerals and produce red and white blood cells. 

via GIPHY

The Functions of Our Bones

•Support – The bones of your body creates a rigid framework that provides structural support form the framework that supports the body.

•Protection – Your bones provide a protective casing around your brain, spinal cord, and vital organs

•Movement – Your bones act as levers that are moved by your muscles to provide movement of body segments.  

•Mineral Storage – reservoir for minerals, especially calcium and phosphate

•Blood Cell Formation – hematopoiesis occurs within the red marrow

•Energy storage – yellow marrow stores fats
Bones provide a lever that provides movement upon muscle contraction. In the animation below, contraction of the bicep muscle causes the forearm to move along the joint axis. 
Your bones act as levers that are moved by your muscles to allow for mobility of different parts of your body. 

Bone Remodeling

​    The trabeculae have three types of bone cells: osteoblasts (immature osteocytes), osteocytes and osteoclasts. 

Osteoblasts function to build new bone for growth and repair by producing layers of new bone tissue composed largely of calcium and phosphate. Osteoblasts become osteocytes when they mature and they remain embedded in the bone tissue.

Osteoclasts are large cells that act to breakdown bone tissue. They destroy old or damaged bone so that it can be repaired and replaced.  This breakdown / buildup cycle is referred to as bone remodeling.  


The Anatomy of a Bone

The bones of the arms and legs in humans are the largest in the body and are known as long bones. Long bones are made up of two types of bone tissue. The diaphysis (central part) of a long bone is composed of compact (cortical) bone. Spongy (cancellous) bone is found at the epiphysis (ends) of long bones and is also found in the pelvic bones, ribs, skull, and the vertebrae. it contains the red bone marrow that makes red blood cells and the yellow bone marrow which stores fats. 

Long Bones

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Bone Marrow - The two types of bone marrow are "red marrow"  and "yellow marrow"

Red Marrow -  Located within the medullary cavity, it consists mainly of hematopoietic  cells that give rise to red blood cells, platelets, and most white of the blood cells of the body.

Yellow Marrow - Located within the medullary cavity, it consists mainly of fat cells.
Articular Cartilage - Articular cartilage is the smooth, white tissue that covers the ends of bones where they come together to form joints. ​
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Long Bones have compact bone on the outer portions of the bone, as well as in the shaft to provide added strength. The inner portions of the ends of long bones will contain spongy bone. 
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The Medullary Cavity - (Sometimes referred to as the Marrow Cavity) makes up part of the central cavity within the diaphysis (bone shaft) and houses red bone marrow (blood cells creation) and/or yellow bone marrow (adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity.

The Periosteum - The periosteum is where new bone growth occurs. It is composed of a layer of dense irregular connective tissue that contains osteoblasts. These osteoblasts are responsible for increasing the width of a long bone and the overall size of the other bone types. 
Nutrient Foramen - All bones possess  foramina (foramen sing.) which are holes or openings for the entrance of the nourishing blood-vessels as well as nerves.  In long bones, the nutrient foramen is located at the shaft and leads into a nutrient canal, which extends into the medullary cavity.
Compact Bone - In long bones, compact bone is found at the diaphysis (shaft_ region of the bone. 

Spongy Bone - In long bones, spongy bone is found at the epiphysis (ends) of the bone. 
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Identify the Main Bones of the Body

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​ The upper leg bone, or thigh bone, is called the femur.
​


                       FEMUR - ANTERIOR VIEW
    FEMUR - POSTERIOR VIEW
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​Femur Anterior View KEY
  1. ​Greater Trochanter
  2. Inner Trochanteric Line
  3. Shaft or Diaphysis
  4. Lateral Epicondyle
  5. Lateral Condyle
  6. Patelar Surface
  7. Head
  8. Neck
  9. Lesser Trochanter
  10. Adductor Tubercle
  11. Medial Epicondyle
  12. ​Medial Condyle
Femur Posterior View KEY
  1. ​Head
  2. Neck
  3. Lesser Trochanter
  4. Medial Supracondylar Line
  5. Abductor Tubercle
  6. Medial Epicondyle
  7. Medial Condyle
  8. Greater Trochanter
  9. Interchanteric  Crest
  10. Gluteal Tuberosity
  11. Linea Aspera
  12. Lateral Supracondylar Line
  13. Lateral Epicondyle
  14. ​Lateral Condyle
  15. Intercondylar Fossa
THE DIAPHYSIS
The diaphysis is also known as the shaft of a long bone. It encompasses most of the long axis of a long bone. 
THE EPIPHYSIS
THE EPIPHYSEAL LINE (PLATE)
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The epiphyseal line exists at the ends of adult long bones, between the diaphysis and the epiphysis. The epiphyseal plate is a disc-like structure composed of hyaline cartilage. Once your bones have fully formed, the epiphyseal line remains as a remnant of the epiphyseal plate that existed as your bones were still growing.

The epiphyseal line is the point at which the epiphysis and the diaphysis meet. This is an important anatomical landmark that defines where the diaphysis ends and the epiphysis begins. 

MEDULLARY CAVITY
ARTICULATE CARTILAGE
​ Articulate Cartilage is found at the epiphysis of long bones, where  it functions to provide a smooth surface for the gliding motion of the joint. Almost every joint in our bodies contains articulate cartilage. ​
NUTRIENT FORAMEN
                                                                                            
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