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    • Organ Systems
    • Portal to the Skeletal system
      • The SKULL ANATOMY
      • the Thoracic Cage
      • the vertebral column
      • The Appendicular Skeleton
      • BONES AND SKELETAL TISSUES
      • joints
    • The Muscular System Portal
      • Muscle Tissue
      • Muscles - Intramuscular Injection Sites - WCU
      • Muscles of the Body - Review
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      • Introduction to the Nervous System
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    • Digestive System
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    • dissection of the fetal pig
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    • Portal to the Skeletal system
    • Endocrine and Homeostasis physio
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    • Course Calendar - BIO 3070
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    • Female Reproductive System
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    • The Male Reproductive System and Male Contraception
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    • In-Vitro Fertilization
    • Infertility
    • Genetics of Reproduction
    • Prenatal and Maternity Care
    • The Pregnant Body
    • fetal development
    • Development of the Nervous System
    • Stages of Labor
    • Postpartum Issues
    • Twins
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    • pH Lab
    • The Chemistry of Cells - ORGANIC
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    • Volcano Project
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    • Online Professionalism
    • Advising Resources
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      • Predation
    • Time Management
  • Environmental Science
    • MIDTERM 2 STUDY GUIDE
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    • ENVS 105 Home Page
      • Midterm 3 Study Guide Population Ecology
      • Ecology II - Communities and Ecosystems
      • Module 1 Assignments
      • Module 2 Assignments
    • Inrtoduction to ENV SCI
    • Historical Perspective of ​Environmental Science
    • Biomes
    • FOOD CHAIN and FOOD WEB
    • Biogeochemical Recycling
    • Evolution - Our Beginning
    • Genetic Inheritance
    • Evolution: How Populations Change over Time
    • Symbiosis
    • Population Ecology
    • Competition in Nature
    • Herbivory
    • Niches
    • Fossil Fuels
  • Environmental Biology Laboratory
    • SOILS AND GROUNDWATER
    • Ecological Roles of Living Organisms
      • The Basics
      • Bacteria - Ecological Roles
      • Protists - Ecological Roles
      • Fungus - Ecological Roles
      • Plantae and Animalia - Ecological Roles
    • Virtual FIELD TRIP TO THE RIO HONDO COLLEGE ​WILDLIFE SANCTUARY - Adaptations to Dry Climates
    • Microscopic Plant Adaptations
    • Natural Selection
    • GROWTH CURVES
    • SOILS AND GROUNDWATER
    • LC50 and LD50
    • How to Make a Solar Water Heater
    • WATER QUALITY ANALYSIS
  • General Biology
    • Characteristics of Life
    • Chemistry of Life - Inorganic
    • The Chemistry of Cells - ORGANIC
    • Introduction to The Cell
    • Photosynthesis and cellular Respiration
    • Cell Membranes and Osmosis
    • The Cell Cycle
    • REGULATION of The Cell Cycle
    • Mitosis
    • Meiosis
    • The Structure of DNA
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  • General Biology Laboratory
    • GENERAL BIOLOGY 101 LABORATORY HOME PAGE
      • Enzymes
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      • Lab 1 - Bacteria, Protista and Fungi
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      • Lab 8 - Enzymes
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      • Lab 10 Fermentation, Aerobic Cellular Respiration and Associated Major Organ Systems
    • GENERAL BIO 1110L Labs
      • lab 2 - CELLS - BIO 111L
      • lab 3 - DIFFUSION and OSMOSIS - BIO 111L
      • lab 4 - The Circulatory System - BIO 111L
      • lab 6 - Photosynthesis and Cellular Respiration
      • lab 7 - Reproduction - BIO 111L
      • DNA, GENES AND GENETIC INHERITANCE
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      • lab 11 - ECOSYSTEMS AND BIODIVERSITY
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    • A History of Human Biology
    • Levels of Organization
    • The Chemistry of Cells - ORGANIC
    • Cells
    • Cartilage SAC
    • BONES AND SKELETAL TISSUES
  • Human Biology Lab
    • Testing for Sugar, Starch and Proteins
    • Osmosis, Diffusion and Filtration
    • buffers
    • OSMOSIS LAB
    • Anatomical Planes
    • Body Cavities and Membranes
    • Anatomical Positions
    • The Appendicular Skeleton
    • The SKULL
    • the Thoracic Cage
    • the vertebral column
  • Human Sexuality
    • Course Information
    • Course Calendar
    • Lesson 1 - Introduction to Human Sexuality
    • Lesson 2 - Genetic Inheritance of Human Sexuality
    • Lesson 3 - The Male Reproductive Tract
    • Lesson 4 - The Female Reproductive Tract
    • Lesson 5 - The Menstrual Cycle
    • Midterm Exam Study Guide
    • Lesson 6 - Fetal Development and Sexual Differentiation
    • Lesson 7 - Disorders of Sexual Development
    • Lesson 8 - Gender Identity and Sexual Attraction
    • Lesson 9 - Fetishism
    • Lesson 10 - Sexuality Throughout the World
    • ​Lesson 11 - Sexuality Through the Ages
    • Lesson 12 - Sexual Harassment, Coercion and Violence
    • Final Exam Study Guide
  • Microbiology PORTAL
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      • ​Intro to Microorganisms
      • Diseases
      • EPIDEMIOLOGY
      • HOST DEFENSES
      • PATHOGENICITY
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      • Bacteria versus Archaea
      • Intro. to Bacteria
      • Viruses and Prions
      • Microbial Genetics
      • Microbial Nutrition and Growth
        • Nutritional Categories
        • Microbial Metabolism
        • CONTROL OF BACTERIA GROWTH AND ANTIBIOTICS
      • Eukaryotic Organisms
      • Archaeal Diversity
      • Prokaryotic and Eukaryotic Cells
      • Bacteria vs Archaeal Structures
      • Taxonomic Classifications
      • Archaea, Bacteria and Eukaryotic Cells
      • MIC- CPP Course Calendar
    • Cell Theory
    • Chemistry of Life
      • Chemical Bonds
      • Chemical Reactions
    • Biofilms
    • Definition of Terms
  • Microbiology Laboratory
    • Cell Culture and Inoculations
    • aseptic technique
    • WET MOUNT
    • Streak Plate
    • Mannitol salt agar (MSA) Test
    • Eosin Methylene Blue (EMB)
    • Blood Agar
    • Dilution Series and Calculations
    • Phage Plaque Assay
    • MICROBIOLOGY UNKNOWN LAB
    • Microbiology Lab -study guide exam one
    • Ex 2 - Microorganisms
    • EX 3 - aseptic technique
    • Ex 4 - Smear Prep
    • Ex 5 - Simple Stains
    • Ex 6 - Negative Staining
    • Ex 8 - Gram Stain
    • Ex 9 - Acid-Fast Stain
    • Ex 10 - Endospore Stain
    • Ex 11 - Motility Test
    • ex 12 -​ Pure culture technique
    • ex 13 - UV Radiation
    • Ex 14 - Enumeration of Bacteria : Standard Plate Count
    • ex - 15 Effects of Temperature on Growth
    • ex 16 - Hand-washing
    • ex 17 - pH and microbial growth
    • ex 18 - Evaluation of Antiseptics
    • ex 19 - Antibiotic Sensitivity : Kirby-Bauer Method
  • HISTOTECHNOLOGY
  • The Brain
  • The Brain
  • The Structure of DNA
  • Contact
  • FUN ZONE
    • GAMES
    • Video Vault
    • Population Ecology - ACTIVITY
    • The Carbon Cycle - ACTIVITY
    • Evolution - ACTIVITY
    • The Cell Game
    • SYMBIOSIS ACTIVITY
    • THE LORAX ACTIVITY
    • Brittney the Kidney
    • From Soup to Poop
    • MITOSIS - THE NURSERY RHYME
    • Verne the Sperm and friends
      • Verne the Sperm pg1
        • Verne the Sperm pg2
        • Verne the Sperm pg3
        • Verne the Sperm pg4
        • Verne the Sperm pg5
  • Lab 6 - The Chemistry of Cells
  • A History of Anatomy
  • List of Pages
    • Microscopes
  • Cell Membranes and Osmosis
  • Chemistry of Life
  • Muscle Movements
  • The Muscles of the Head, Trunk and Shoulders
  • The Muscles of the Limbs
  • Nervous Tissue
  • The Brain - Anat and Physiology
  • Instructions for Taking BIO 3070
  • MTH 121 Algebra A - Course Schedule and Info
  • Laboratory Calendar CMC Spring 2019
  • Genetics Lab
  • Chemistry and Conversions Lab
  • Digestion and Enzymes Lab
  • Endocrine and Homeostasis Lab
  • Muscles and Reflexes Lab
  • Sensory Lab
  • Immunohistochemistry
  • Blood Lab
  • Heart Rate, Blood Pressure, Electrocardiogram Lab
  • Respiratory Lab
  • Lab 11 Renal Lab
  • Blood Typing Game
  • Body Systems Interactive
  • Ch 9 - The Central Nervous System
  • Ch 10 - Sensory Systems
  • Neuron Virtual Laboratory
  • Virtual Eye Lab
  • Virtual pH Lab
  • Chemical Bonds Virtual Lab
  • Beer's Law Virtual Lab
  • Build-an-Atom Virtual Lab
  • Diffusion Virtual Lab
  • Ohm's Law Virtual Lab
  • New Page
  • Ch 8 - Nervous System

MITOSIS​​

MITOSIS​

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Watch My Video on the Cell Cycle and Mighty Mitosis!

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Mitosis Study Guide

Picture

​WHY DO WE DO MITOSIS?

 All the Cells of your Body (except for your oocytes or spermatozoa) reproduce by MITOSIS!

We need mitosis for…

    1.  Growth

    2.  Repair
                 
    3.  Replacement

Picture
Picture
Mitosis for Wound Repair
​

     When you are an adult, your body will still undergo mitosis for cell repair and cell replacement. Cells react and respond to changing environments. How does your body know when it need to grown more cells to heal a wound? Cells communicate to each other using chemical signals. When you cut yourself, the cells along the edge notice that their neighbor is gone. The cell responds by will entering the cell cycle and mitosis to make more cells to fill in the ‘gap’.
 

Quick Review

The Cell Cycle has 2 Main Parts
  • Interphase
  • Mitosis

Interphase has 3 parts
  • G1 (Gap 1)
  • S-Phase (DNA Synthesis)
  • G2 (Gap 2)

Mitosis has 4 phases
  • Prophase
  • Metaphase
  • Anaphase
  • Telophase

The Cell Cycle has 3 checkpoints
  •  G1 checkpoint is at the end of G1
  •  G2 checkpoint is at the end of G2
  •  M checkpoint is toward the end of metaphase, before anaphase of mitosis begins

The Cell Cycle

Picture

Interphase ​

    Interphase includes G1, S and G2 phases of the cell cycle. The cell cycle starts with G1. Then in S-Phase DNA synthesis occurs. Here is where the cell makes copies of its DNA so the chromosomes in the nucleus each consist of two connected copies, called sister chromatids.

    You can’t see the chromosomes under a microscope at this point, because they are still in their long, stringy, decondensed form. Chromosomes in the decondensed form are called chromatin.

     When you look at a plant or animal cell during mitosis, you can only see the cell membrane, the nucleus, the nuclear envelope, and perhaps the nucleolus. 




Picture
Microscope Slide of Animal Cell During Interphase
Picture
Microscope Slide of a Plant Cell During Interphase
    After interphase is complete, MITOSIS BEGINS! Mitosis is the asexual process of cell reproduction (cell division) in which one “parent” cell divides to produce two new “daughter” cells.  The daughter cells are clones of the parent cell. In other words, they are genetically identical to the parent.
Picture


Mitosis has 4 phases
  1. Prophase
  2. Metaphase
  3. Anaphase
  4. Telophase

Prophase

Picture
Microscope Slide of Animal Cell During Prophase
  • ​DNA condenses to form chromosomes.
  • Centrioles and spindles form
  • Nuclear envelope (membrane) begins to break up.
Picture
Microscope Slide of Plant Cell in Prophase
     During interphase, the DNA is not visible under a microscope. The DNA during interphase is in a decondensed state and is referred to as chromatin. During prophase, chromatin condenses to become visible chromosomes that can be seen with a compound microscope. In the plant and animal slide, you can see darkened strand that begin to appear as prophase progresses. These are the chromosomes condensing! You may also see that the nuclear envelope is no longer distinct, indicating the nuclear envelope is breaking up. Breaking up the nuclear envelope is necessary to allow the spindle apparatus to connect to the kinetichores on each sister chromatid. 

Metaphase

Picture
Microscope Slide of Animal Cell During Metaphase
Picture
Microscope Slide of Plant Cell During Metaphase
  • The spindle (or spindle apparatus) attaches to the kinetochores of the chromosomes and lines the chromosomes up along the midline at the metaphase plate. 
  • Remember that each chromosome at this stage is composed of 2 genetically identcal sister chromatids. 
  • Each of the sister chromatids has its own kinetichore (located at its center) that the spindle will connect to. 
Picture

Anaphase

  • The spindle pulls sister chromatids to opposite sides of the cell.
  • The spindle apparatus is connected to the centrioles that lie at the poles of the cell. ​
Picture
Microscope Slide of a Plant Cell During Anaphase
Picture
Microscope Slide of an Animal Cell During Anaphase
Picture
Illustration of a Cell Undergoing Anaphase by ScientistCindy
  • The microtubules that make up the spindle shorten and pull the sister chromatids toward each of the centrioles. ​

Telophase


  • The chromosomes decondense back into chromatin form.
  • Spindle disappears.
  • Nuclear envelope (membrane ) reforms.
Picture
Microscope Slide of an Animal Cell Undergoing Telophase
Picture
Illustration of Telophase by ScientistCindy
Picture
Microscope Slide of Plant Cell Undergoing Telophase

Cytokinesis

Picture
Cytokinesis occurs after telophase and is the process of proteins “pinching” the single cell into 2 newly formed daughter cells. It is not a phase itself, but is the name of the final step at the end of telophase that creates two separate daughter cells!


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